"Association of the Anxiogenic and Alerting Effects of Caffeine with ADORA2A and ADORA1 Polymorphisms and Habitual Level of Caffeine Consumption."Peter J Rogers, Christa Hohoff, Susan V Heatherley, Emma L Mullings, Peter J Maxfield, Richard P Evershed, Jürgen Deckert and David J Nutt.Neuropsychopharmacology advance online publication, June 2, 2010.DOI:10.1038/npp.2010.71Source: Bristol University.Written by: Catharine Paddock, PhD Copyright: Medical News Today Not to be reproduced without permission of Medical News Today
A UK-led study suggests the notion that caffeine makes us more alert is more imagined than real and that frequent coffee drinkers develop a tolerance to both its stimulatory and anxiety-producing effects.
You can read about the study led by researchers at Bristol University in the 2 June advanced online issue of the journal Neuropsychopharmacology.
While frequent coffee drinkers may feel alerted by coffee, the study suggests this is just a sign of reversing the fatigue effect of caffeine withdrawal, and given that caffeine also increases anxiety and blood pressure, there is no net advantage.
Co-lead author Dr Peter Rogers, of the Department of Experimental Psychology at Bristol told the media that:
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